经过与一十一（神木隆之介 饰）的恶战，濑文焚流（加濑亮 饰）身受重伤，命几不保。在此期间，青池里子（栗山千明 饰）随女儿小润（森山树 饰）悄然离开医院；而各国政要的一次关于简单计划的秘密会议上，自称卑弥呼的日本代表抹杀所有人，他代表SPEC持有者正式向普通人类宣战。世态险恶的当下，濑文急急出院，和当麻纱绫（户田惠梨香 饰）一同调查青池母女的行踪。而野野村组长（龙雷太 饰）则独自行动，查找简单计划病毒疫苗的下落。新的SPEC持有者交替登场，残酷的杀戮却从未停止。关于前人类的秘密昭然若揭，惨烈浩大的人种战争即将拉开序幕…… 本片为SPEC系列完结篇的前篇。
一伙年轻盗贼(西恩威廉史考特等)举办了一场疯狂的摇头派对掩人耳目，他们计划暗中窃入隔壁的银行盗取现款……由于音波互相干扰，警铃声响将被抵销…… 班被债主迫得走投无路，决定与几名友人爆窃银行。他们开了场疯狂的摇头派对掩人耳目，然后溜进隔壁的银行偷窃，利用音波互相干扰来抵销警铃声响。怎料波折重重，这群笨贼屡次失手，国际刑警突然出现，死对头又走来搞破坏……
Wealthy Rollo Treadway (Buster Keaton) suddenly decides to propose to his neighbor across the street, Betsy O'Brien (Kathryn McGuire), and sends his servant to book passage for a honeymoon sea cruise to Honolulu. When Betsy rejects his sudden offer however, he decides to go on the trip anyway, boarding without delay that night. Because the pier number is partially covered, he ends up on the wrong ship, the Navigator, which Betsy's rich father (Frederick Vroom) has just sold to a small country at war. Agents for the other small nation in the conflict decide to set the ship adrift that same night. When Betsy's father checks up on the ship, he is captured and tied up by the saboteurs. Betsy hears his cry for help and boards the ship to look for him, just before it is cut loose. The Navigator drifts out into the Pacific Ocean. The two unwitting passengers eventually find each other. At first, they have great difficulty looking after themselves, but adapt after a few weeks. At one point, they sight a navy ship and hoist a brightly-colored flag, not realizing it signals that the ship is under quarantine. As a result, the other vessel turns away. Finally, the ship grounds itself near an inhabited tropical island and springs a leak. While Rollo dons a deep sea diving suit and submerges to patch the hole, the black natives canoe out and take Betsy captive. When Rollo emerges from the ocean, the natives are scared off, enabling him to rescue Betsy and take her back to the ship. The natives return and try to board the ship. After a fierce struggle, Rollo and Betsy try to escape in a small dinghy. It starts to sink, and the natives swiftly overtake them in their canoes. Just when all seems lost, a navy submarine surfaces right underneath them and they are saved.
讲述了一群年轻的上班族，他们发现了一个惊人的秘密，他们的大老板曾经是一个连环杀手。他们应该如何面对？
